AFTER DETECTION COMES THE PATHWAY.
Screening finds the keratoconic eye; this module plans what happens next — is it progressing, which cross-linking protocol does this thickness allow, do ring segments have a place, and can your femtosecond laser actually cut the tunnel?
PROGRESSION BY CONSENSUS, NOT IMPRESSION
Progression requires at least two of three documented changes — anterior steepening, posterior steepening, pachymetric thinning — per the Global Consensus, which deliberately sets no numerical cut-off.[2] RLES AI Mobile Interfacelies ≥ 1.0 D of Kmax change over 12 months as its own operational threshold for documented anterior steepening; the final progression judgement remains clinical. Because pediatric keratoconus may progress rapidly, early CXL evaluation is prioritised when documented progression or high-risk features are present; prophylactic CXL without documented progression is not supported. The report states which criteria were met and which data are missing.
THE CXL LADDER, BY THICKNESS AND BY YOUR DEVICE
- ≥ 400 µm → Dresden 3 mW/30 min[1] or accelerated 9 mW/10 min[4][5] (equivalent evidence)
- 320–399 µm → hypoosmolar riboflavin or contact-lens-assisted CXL, with intraoperative ≥ 400 µm confirmation before UVA
- < 320 µm → CXL is off the table; the report says so and redirects
- Your CXL device and riboflavin kit are registered once — protocols are then written only in your device’s approved modes and your kit’s soak scheme, never from a generic table
RINGS: BRAND GEOMETRY AND TUNNEL CAPABILITY
CAIRS and ICRS are compared honestly — allograft segments, with extrusion not reported in early series,[3] versus established synthetic nomograms. Segment planning is brand-specific (Keraring, Ferrara, Intacs geometries differ) and is only produced once the brand is known. The femtosecond tunnel capability of your registered laser is checked against its actual labelling — a device without tunnel capability routes to manual dissection or referral. Beyond the limits (Kmax > 70 D, central scarring), a DALK/PK referral report is produced. Combined ring+CXL sequencing notes that segments placed after CXL act on stiffened stroma with reduced effect.
FREQUENTLY ASKED QUESTIONS
RLES AI runs as a mobile interface on your phone — nothing to install from a store, reports in minutes. The final clinical decision always rests with the surgeon.
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- Wollensak G et al. Riboflavin/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 2003;135:620-7. PMID: 12719068
- Gomes JA et al. Global consensus on keratoconus and ectatic diseases. Cornea 2015;34:359-69. PMID: 25738235
- Jacob S et al. Corneal Allogenic Intrastromal Ring Segments (CAIRS) Combined With Corneal Cross-linking for Keratoconus. J Refract Surg. 2018;34(5):296-303. doi:10.3928/1081597X-20180223-01 PMID: 29738584
- Kurt T, Ozgurhan EB, Yildirim Y, Akcay BIS, Cosar MG, Bozkurt E, Taskapili M. Accelerated (18 mW/cm2) Corneal Cross-Linking for Progressive Keratoconus: 18-Month Results. J Ocul Pharmacol Ther. 2016;32(4):186-91. doi:10.1089/jop.2015.0127 PMID: 27027668
- Ozgurhan EB, Celik U, Bozkurt E, Demirok A. Evaluation of subbasal nerve morphology and corneal sensation after accelerated corneal collagen cross-linking treatment on keratoconus. Curr Eye Res. 2015;40(5):484-9. doi:10.3109/02713683.2014.932387 PMID: 24979260